Complement activation in atypical hemolytic uremic syndrome and scleroderma renal crisis: a critical analysis of pathophysiology

ABSTRACT Scleroderma is an autoimmune disease that affects multiple systems. While pathophysiologic mechanisms governing the development of scleroderma are relatively poorly understood, advances in our understanding of the complement system are clarifying the role of complement pathways in the devel...

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Bibliographic Details
Main Authors: Roman Zuckerman, Arif Asif, Eric J. Costanzo, Tushar Vachharajani
Format: Article
Language:English
Published: Sociedade Brasileira de Nefrologia 2018-05-01
Series:Brazilian Journal of Nephrology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002018005008102&lng=en&tlng=en