Multifaceted Control of GR Signaling and Its Impact on Hepatic Transcriptional Networks and Metabolism

Multifaceted Control of GR Signaling and Its Impact on Hepatic Transcriptional Networks and Metabolism

Glucocorticoids (GCs) and the glucocorticoid receptor (GR) are important regulators of development, inflammation, stress response and metabolism, demonstrated in various diseases including Addison's disease, Cushing's syndrome and by the many side effects of prolonged clinical administrati...

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Bibliographic Details
Main Authors: Stine M. Præstholm, Catarina M. Correia, Lars Grøntved
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Endocrinology
Subjects:
Glucocorticoid receptor
chromatin
transcription
metabolism
liver
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.572981/full

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