<it>Wnt-5a </it>occludes Aβ oligomer-induced depression of glutamatergic transmission in hippocampal neurons

<it>Wnt-5a </it>occludes Aβ oligomer-induced depression of glutamatergic transmission in hippocampal neurons

<p>Abstract</p> <p>Background</p> <p>Soluble amyloid-β (Aβ;) oligomers have been recognized to be early and key intermediates in Alzheimer's disease (AD)-related synaptic dysfunction. Aβ oligomers block hippocampal long-term potentiation (LTP) and impair rodent spa...

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Bibliographic Details
Main Authors:	Inestrosa Nibaldo C, Fuenzalida Marco, Bonansco Christian, Godoy Juan A, Farías Ginny G, Cerpa Waldo
Format:	Article
Language:	English
Published:	BMC 2010-01-01
Series:	Molecular Neurodegeneration
Online Access:	http://www.molecularneurodegeneration.com/content/5/1/3

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