Increased Expression of Resistin in MicroRNA-155-Deficient White Adipose Tissues May Be a Possible Driver of Metabolically Healthy Obesity Transition to Classical Obesity

Increased Expression of Resistin in MicroRNA-155-Deficient White Adipose Tissues May Be a Possible Driver of Metabolically Healthy Obesity Transition to Classical Obesity

We reported that microRNA-155 (miR-155) deficiency in ApoE-/- mice yields a novel metabolically healthy obese (MHO) model, which exhibits improved atherosclerosis but results in obesity, non-alcoholic fatty liver disease (NAFLD) without insulin resistance. Using experimental data mining approaches c...

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Bibliographic Details
Main Authors: Candice Johnson, Charles Drummer, Anthony Virtue, Tracy Gao, Susu Wu, Miguel Hernandez, Lexy Singh, Hong Wang, Xiao-Feng Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Physiology
Subjects:
microRNAs
atherosclerosis
diabetes
fatty liver disease
obesity
resistin
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01297/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01297/full

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