Evaluation of TorsinA as a target for Parkinson disease therapy in mouse models.

Parkinson disease (PD) is a common and disabling disorder. No current therapy can slow or reverse disease progression. An important aspect of research in this field is target validation, a systematic approach to evaluating the likelihood that modification of a certain molecule, mechanism or biologic...

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Bibliographic Details
Main Authors: Xinru Li, Jenny Lee, Dee Parsons, Karen Janaurajs, David G Standaert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3503809?pdf=render