Influenza A Virus Induces Autophagy by Its Hemagglutinin Binding to Cell Surface Heat Shock Protein 90AA1

Influenza A Virus Induces Autophagy by Its Hemagglutinin Binding to Cell Surface Heat Shock Protein 90AA1

Autophagy can be utilized by the influenza A virus (IAV) to facilitate its replication. However, whether autophagy is induced at the stage of IAV entry is still unclear. Here, we report that IAV induces autophagy by hemagglutinin (HA) binding to heat shock protein 90AA1 (HSP90AA1) distributed on the...

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Bibliographic Details
Main Authors: Xingbo Wang, Tuyuan Zheng, Lulu Lin, Yina Zhang, Xiran Peng, Yan Yan, Jing Lei, Jiyong Zhou, Boli Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Microbiology
Subjects:
influenza A virus
hemagglutinin (HA)
HSP90AA1
virus entry
autophagy
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.566348/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.566348/full

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