Rendezvous at Plasma Membrane: Cellular Lipids and tRNA Set up Sites of HIV-1 Particle Assembly and Incorporation of Host Transmembrane Proteins

The HIV-1 structural polyprotein Gag drives the virus particle assembly specifically at the plasma membrane (PM). During this process, the nascent virion incorporates specific subsets of cellular lipids and host membrane proteins, in addition to viral glycoproteins and viral genomic RNA. Gag binding...

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Bibliographic Details
Main Authors: Dishari Thornhill, Tomoyuki Murakami, Akira Ono
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
RNA
Online Access:https://www.mdpi.com/1999-4915/12/8/842