Using miRNA‐mRNA Interaction Analysis to Link Biologically Relevant miRNAs to Stem Cell Identity Testing for Next‐Generation Culturing Development

Using miRNA‐mRNA Interaction Analysis to Link Biologically Relevant miRNAs to Stem Cell Identity Testing for Next‐Generation Culturing Development

Therapeutic benefit of stem cells has been demonstrated in multiple disease models and clinical trials. Robust quality assurance is imperative to make advancements in culturing procedures to enable large‐scale cell manufacturing without hampering therapeutic potency. MicroRNAs (miRNAs or miRs) are s...

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Bibliographic Details
Main Authors: Marian A.E. Crabbé, Kristel Gijbels, Aline Visser, David Craeye, Sara Walbers, Jef Pinxteren, Robert J. Deans, Wim Annaert, Bart L.T. Vaes
Format: Article
Language:English
Published: Wiley 2016-06-01
Series:Stem Cells Translational Medicine
Subjects:
MicroRNA profiling
Multipotent adult progenitor cell
Mesenchymal stem cell
Bioreactor
Xenobiotic-free
Cell comparability testing
Online Access:https://doi.org/10.5966/sctm.2015-0154

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