Inhibition of Phosphoinositide 3-Kinase/Protein Kinase B Signaling Hampers the Vasopressin-dependent Stimulation of Myogenic Differentiation

Inhibition of Phosphoinositide 3-Kinase/Protein Kinase B Signaling Hampers the Vasopressin-dependent Stimulation of Myogenic Differentiation

Arginine-vasopressin (AVP) promotes muscle differentiation, hypertrophy, and regeneration through the combined activation of the calcineurin and Calcium/Calmodulin-dependent Protein Kinase (CaMK) pathways. The AVP system is impaired in several neuromuscular diseases, suggesting that AVP may act as a...

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Bibliographic Details
Main Authors: Silvia Sorrentino, Alessandra Barbiera, Gabriella Proietti, Gigliola Sica, Sergio Adamo, Bianca Maria Scicchitano
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
skeletal muscle
LY294002
b-HLH-MRFs
HDACs
mTOR
CaMK
Online Access:https://www.mdpi.com/1422-0067/20/17/4188

Internet

https://www.mdpi.com/1422-0067/20/17/4188

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