In Vitro and In Vivo Antimalarial Activity of LZ1, a Peptide Derived from Snake Cathelicidin

In Vitro and In Vivo Antimalarial Activity of LZ1, a Peptide Derived from Snake Cathelicidin

Antimalarial drug resistance is an enormous global threat. Recently, antimicrobial peptides (AMPs) are emerging as a new source of antimalarials. In this study, an AMP LZ1 derived from snake cathelicidin was identified with antimalarial activity. In the in vitro antiplasmodial assay, LZ1 showed stro...

Full description

Bibliographic Details
Main Authors: Yaqun Fang, Xiaoqin He, Pengcheng Zhang, Chuanbin Shen, James Mwangi, Cheng Xu, Guoxiang Mo, Ren Lai, Zhiye Zhang
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Toxins
Subjects:
antimicrobial peptide
malaria
cytokine
pyruvate kinase
ATP
Online Access:https://www.mdpi.com/2072-6651/11/7/379

Similar Items

Similar Items