Glucocorticoid Inhibition of Estrogen Regulation of the Serotonin Receptor 2B in Cardiomyocytes Exacerbates Cell Death in Hypoxia/Reoxygenation Injury

Glucocorticoid Inhibition of Estrogen Regulation of the Serotonin Receptor 2B in Cardiomyocytes Exacerbates Cell Death in Hypoxia/Reoxygenation Injury

Background Stress has emerged as an important risk factor for heart disease in women. Stress levels have been shown to correlate with delayed recovery and increased mortality after a myocardial infarction. Therefore, we sought to investigate if the observed sex‐specific effects of stress in myocardi...

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Bibliographic Details
Main Authors: Hemangini A. Dhaibar, Natalie G. Carroll, Shripa Amatya, Lilly Kamberov, Pranshu Khanna, A. Wayne Orr, Steven R. Bailey, Robert H. Oakley, John A. Cidlowski, Diana Cruz‐Topete
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiomyocytes
estrogen
gene regulation
glucocorticoids
serotonin receptor 2b
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.015868

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