The RB Tumor Suppressor Positively Regulates Transcription of the Anti-angiogenic Protein NOL7

The expression of the angiogenic phenotype is regulated by a balance of pro-angiogenic and anti-angiogenic factors released into the tumor microenvironment. Nuclear protein 7 (NOL7), a novel tumor suppressor, acts as a master regulator of angiogenesis by downregulating pro-angiogenic factors and up...

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Bibliographic Details
Main Authors: Tanmayi P. Mankame, Mark W. Lingen
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612800571