Physiologically Based Pharmacokinetic Modeling in Pediatric Drug Development: A Clinician’s Request for a More Integrated Approach
Main Authors: | Karel Allegaert, Anne Smits, Johannes N. van den Anker |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
|
Series: | Journal of Biomedicine and Biotechnology |
Online Access: | http://dx.doi.org/10.1155/2012/103763 |
Similar Items
-
A Physiology-Based Pharmacokinetic Framework to Support Drug Development and Dose Precision During Therapeutic Hypothermia in Neonates
by: Anne Smits, et al.
Published: (2020-05-01) -
Mechanistic Coupling of a Novel in silico Cotyledon Perfusion Model and a Physiologically Based Pharmacokinetic Model to Predict Fetal Acetaminophen Pharmacokinetics at Delivery
by: Paola Mian, et al.
Published: (2021-09-01) -
Creatinine Trends to Detect Ibuprofen-Related Maturational Adverse Drug Events in Neonatal Life: A Simulation Study for the ELBW Newborn
by: Tamara van Donge, et al.
Published: (2021-01-01) -
Adverse drug events in pediatric intensive care are common, but improvement strategies exist and are effective
by: Karel Allegaert -
Physiologically Based Pharmacokinetic Modeling and Simulation in Pediatric Drug Development
by: A R Maharaj, et al.
Published: (2014-11-01)