Depression-like behavior induced by nesfatin-1 in rats: involvement of increased immune activation and imbalance of synaptic vesicle proteins

Depression-like behavior induced by nesfatin-1 in rats: involvement of increased immune activation and imbalance of synaptic vesicle proteins

Depression is a multicausal disorder and has been associated with metabolism regulation and immuno-inflammatory reaction. The anorectic molecule nesfatin-1 has recently been characterized as a potential mood regulator, but its precise effect on depression and the possible mechanisms remain unknown,...

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Bibliographic Details
Main Authors: Ge eJinfang, Xu eYa-Yun, Qin eGan, Peng eYao-Nan, Chao-Feng eZhang, Xing-Rui eLiu, Li-Chuan eLiang, Zhong-Zheng eWang, Chen eFei-Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Neuroscience
Subjects:
Depression
C-reactive protein (CRP)
nesfatin-1
Interleukin 6 (IL-6)
Hypothalamic-pituitary-adrenal axis (HPA)
synapsinⅠ
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00429/full

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