Activity-Based Protein Profiling Reveals Potential Dasatinib Targets in Gastric Cancer

Dasatinib is a multi-target kinase inhibitor, whose targets include BCR-ABL, SRC family kinases, and various cancer kinases. The elevated SRC activity in gastric cancer (GC) has prompted the need for the therapeutic application of dasatinib in GC. We observed that the efficacy of dasatinib varied wi...

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Bibliographic Details
Main Authors: Kyoung-Min Choi, Eunji Cho, Geul Bang, Seong-Jae Lee, Boram Kim, Ji-Hee Kim, Seo-Gyu Park, Eun Hee Han, Young-Ho Chung, Jin Young Kim, Eunjung Kim, Jae-Young Kim
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/23/9276