Lack of association of B-type raf kinase V600E mutation with high-risk tumor features and adverse outcome in conventional and follicular variants of papillary thyroid carcinoma

Lack of association of B-type raf kinase V600E mutation with high-risk tumor features and adverse outcome in conventional and follicular variants of papillary thyroid carcinoma

Introduction: Somatic B-type Raf kinase (BRAF) V600E mutation in exon 15 was frequently found in high frequencies associated with papillary thyroid cancer (PTC). The phenotype of these cancers expressed aggressive clinical and pathological features. The present study aimed to assess the prevalence...

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Bibliographic Details
Main Authors: C Gopalakrishnan Nair, Misha Babu, Lalitha Biswas, Pradeep Jacob, Riju Menon, A K Revathy, Krishnanunni Nair
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Indian Journal of Endocrinology and Metabolism
Subjects:
B-type Raf kinase V600E mutation
differentiated thyroid cancer
genetic features of thyroid cancer
papillary thyroid cancer
Online Access:http://www.ijem.in/article.asp?issn=2230-8210;year=2017;volume=21;issue=2;spage=329;epage=333;aulast=Nair

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