Long intervals of stasis punctuated by bursts of positive selection in the seasonal evolution of influenza A virus
<p>Abstract</p> <p>Background</p> <p>The interpandemic evolution of the influenza A virus hemagglutinin (HA) protein is commonly considered a paragon of rapid evolutionary change under positive selection in which amino acid replacements are fixed by virtue of their effe...
Main Authors: | Koonin Eugene V, Holmes Edward C, Viboud Cecile, Wolf Yuri I, Lipman David J |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-10-01
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Series: | Biology Direct |
Online Access: | http://www.biology-direct.com/content/1/1/34 |
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