Interleukin-6 signalling in health and disease [version 1; peer review: 3 approved]

Biochemically, interleukin-6 belongs to the class of four-helical cytokines. The cytokine can be synthesised and secreted by many cells. It acts via a cell surface-expressed interleukin-6 receptor, which is not signalling competent. This receptor, when complexed with interleukin-6, associates with t...

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Bibliographic Details
Main Author: Stefan Rose-John
Format: Article
Language:English
Published: F1000 Research Ltd 2020-08-01
Series:F1000Research
Online Access:https://f1000research.com/articles/9-1013/v1