Clozapine-induced mitochondria alterations and inflammation in brain and insulin-responsive cells.

BACKGROUND: Metabolic syndrome (MetS) is a constellation of factors including abdominal obesity, hyperglycemia, dyslipidemias, and hypertension that increase morbidity and mortality from diabetes and cardiovascular diseases and affects more than a third of the population in the US. Clozapine, an aty...

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Bibliographic Details
Main Authors: Verόnica Contreras-Shannon, Dylan L Heart, R Madelaine Paredes, Erica Navaira, Gabriel Catano, Shivani Kaushal Maffi, Consuelo Walss-Bass
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3604003?pdf=render