Functional-network-based gene set analysis using gene-ontology.

Functional-network-based gene set analysis using gene-ontology.

To account for the functional non-equivalence among a set of genes within a biological pathway when performing gene set analysis, we introduce GOGANPA, a network-based gene set analysis method, which up-weights genes with functions relevant to the gene set of interest. The genes are weighted accordi...

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Bibliographic Details
Main Authors: Billy Chang, Rafal Kustra, Weidong Tian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3572115?pdf=render

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