Protective effect of a phytocompound on oxidative stress and DNA fragmentation against paracetamol-induced liver damage

Protective effect of a phytocompound on oxidative stress and DNA fragmentation against paracetamol-induced liver damage

The hepatoprotective potential DTS (1.5 g/kg bw, Densh-ici-to-Chiusei, Kyotsu Jigyo, Tokyo, Japan) was evaluated against either toxic (1.5 g/kg bw) and sub-toxic (150 mg/kg bw) dosage of paracetamol-induced liver injury in Sprague-Dawley rat. Paracetamol intoxication caused a reduction of serum tota...

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Bibliographic Details
Main Authors: Francesco Marotta, Prof., MD, PhD, Hariom Yadav, Upendra Gumaste, A.m.r. Helmy, Shalini Jain, Emilio Minelli
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Annals of Hepatology
Subjects:
Paracetamol
oxidative stress
DNA fragmentation
DTS
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119318113

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