Degradation of GRK2 and AKT is an early and detrimental event in myocardial ischemia/reperfusionResearch in context
Background: Identification of signaling pathways altered at early stages after cardiac ischemia/reperfusion (I/R) is crucial to develop timely therapies aimed at reducing I/R injury. The expression of G protein-coupled receptor kinase 2 (GRK2), a key signaling hub, is up-regulated in the long-term i...
Main Authors: | Petronila Penela, Javier Inserte, Paula Ramos, Antonio Rodriguez-Sinovas, David Garcia-Dorado, Federico Mayor, Jr |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-10-01
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Series: | EBioMedicine |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352396419306231 |
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