Amplification of the MYC Gene in Osteosarcoma Secondary to Paget's Disease of Bone

Purpose. In a previous series of 25 human osteosarcoma samples studied for MYC gene amplification, we found amplification in two cases (8%), including one arising in association with Paget's disease (pagetic osteosarcoma). Based on this observation, we further investigated the prevalence of MYC...

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Main Authors:	Takafumi Ueda, John H. Healey, Andrew G. Huvos, Marc Ladanyi
Format:	Article
Language:	English
Published:	Hindawi Limited 1997-01-01
Series:	Sarcoma
Online Access:	http://dx.doi.org/10.1080/13577149778209

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spelling	doaj-856b43dc02984e5c84e0549966b6ce412020-11-24T23:17:04ZengHindawi LimitedSarcoma1357-714X1369-16431997-01-0113-413113410.1080/13577149778209Amplification of the MYC Gene in Osteosarcoma Secondary to Paget's Disease of BoneTakafumi Ueda0John H. Healey1Andrew G. Huvos2Marc Ladanyi3Department of Surgery, Orthopaedic Service, Memorial Sloan-Kettering Cancer Center, New York, USADepartment of Surgery, Orthopaedic Service, Memorial Sloan-Kettering Cancer Center, New York, USADepartment of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York 10021, NY, USADepartment of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York 10021, NY, USAPurpose. In a previous series of 25 human osteosarcoma samples studied for MYC gene amplification, we found amplification in two cases (8%), including one arising in association with Paget's disease (pagetic osteosarcoma). Based on this observation, we further investigated the prevalence of MYC gene amplification in pagetic osteosarcomas.http://dx.doi.org/10.1080/13577149778209
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Takafumi Ueda John H. Healey Andrew G. Huvos Marc Ladanyi
spellingShingle	Takafumi Ueda John H. Healey Andrew G. Huvos Marc Ladanyi Amplification of the MYC Gene in Osteosarcoma Secondary to Paget's Disease of Bone Sarcoma
author_facet	Takafumi Ueda John H. Healey Andrew G. Huvos Marc Ladanyi
author_sort	Takafumi Ueda
title	Amplification of the MYC Gene in Osteosarcoma Secondary to Paget's Disease of Bone
title_short	Amplification of the MYC Gene in Osteosarcoma Secondary to Paget's Disease of Bone
title_full	Amplification of the MYC Gene in Osteosarcoma Secondary to Paget's Disease of Bone
title_fullStr	Amplification of the MYC Gene in Osteosarcoma Secondary to Paget's Disease of Bone
title_full_unstemmed	Amplification of the MYC Gene in Osteosarcoma Secondary to Paget's Disease of Bone
title_sort	amplification of the myc gene in osteosarcoma secondary to paget's disease of bone
publisher	Hindawi Limited
series	Sarcoma
issn	1357-714X 1369-1643
publishDate	1997-01-01
description	Purpose. In a previous series of 25 human osteosarcoma samples studied for MYC gene amplification, we found amplification in two cases (8%), including one arising in association with Paget's disease (pagetic osteosarcoma). Based on this observation, we further investigated the prevalence of MYC gene amplification in pagetic osteosarcomas.
url	http://dx.doi.org/10.1080/13577149778209
work_keys_str_mv	AT takafumiueda amplificationofthemycgeneinosteosarcomasecondarytopagetsdiseaseofbone AT johnhhealey amplificationofthemycgeneinosteosarcomasecondarytopagetsdiseaseofbone AT andrewghuvos amplificationofthemycgeneinosteosarcomasecondarytopagetsdiseaseofbone AT marcladanyi amplificationofthemycgeneinosteosarcomasecondarytopagetsdiseaseofbone
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Amplification of the MYC Gene in Osteosarcoma Secondary to Paget's Disease of Bone

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