Evaluating the Correlation of Systemic Inflammatory Response Syndrome with Mortality and Morbidity in Critically Ill Obstetric Patients in ICU

• Main Author: M Jabalameli
• Format: Article
• Language: fas
• Published: Qom University of Medical Sciences 2012-05-01
• Series: Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
• Online Access: http://journal.muq.ac.ir/en/index.php/jmuqen/article/view/103
• ISSN: 1735-7799; 2008-1375

<p><strong><em>Background and Objectives:</em></strong> Systemic inflammatory response syndrome (SIRS) is a relatively accurate predictor of outcome in critically ill patients treated in medical/surgical ICU. However, there are few data on the incidence of SIRS and its effect on outcome in obstetric patients. The aim of this study was to assess the incidence of SIRS and its relationships with mortality and morbidity in obstetric patients admitted to ICU.<strong></strong></p><p><strong><em>Methods:</em></strong> Routine Data Base study was conducted on documents of all obstetric patients admitted to ICUs of two medical teaching centers of Isfahan University of Medical Sciences from Oct 2005 to Feb 2006. Information including SIRS criteria factors, complications, length of ICU stay and mortality were gathered from patients medical records. According to SIRS criteria, patients were categorized into SIRS positive and SIRS negative with comparing the morbidity and mortality rates between the two groups. X² test was used for comparing mortality rate and complications between SIRS positive and negative, and Mann-whitney test was used for comparing the length of stay. Correlation coefficient of Spiermann was applied for assessing SIRS score with mortality rate and complications. In all tests, P<0.05 was considered statistically significant.</p><p><strong><em>Results:</em></strong> In this study, out of 102 available medical records, the data of 82 were complete, and hence were included in the study. Based on the criteria, 68(83%) had SIRS. The difference in mortality rate was not statistically significant, but the two groups were significantly different in complications especially cardiovascular and coagulation complications which were more frequent in SIRS positive patients (P<0.05). The length of stay in SIRS positive patients was statistically more than SIRS negative cases (P<0.05). There was a positive correlation between SIRS score and mortality rate but it was not statistically significant (r=0.189, P=0.089).</p><p><strong><em>Conclusion:</em></strong> Based on the results of this study, the incidence of SIRS in obstetric patients admitted to ICU is remarkable and associated with increasing morbidity. So, it can be used as a predictive factor for outcomes in obstetric patients treated in ICU.</p>