Allicin May Promote Reversal of T-Cell Dysfunction in Periodontitis via the <i>PD-1</i> Pathway

Allicin May Promote Reversal of T-Cell Dysfunction in Periodontitis via the <i>PD-1</i> Pathway

We evaluated the role of allicin in periodontitis using an in silico and in vitro design. An in silico docking analysis was performed to assess the plausible interactions between allicin and <i>PD-L1</i>. The cytokine profile of gingival crevicular fluid (GCF) samples obtained from perio...

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Bibliographic Details
Main Authors: Shankargouda Patil, Mohammed E. Sayed, Maryam H. Mugri, Khalaf F. Alsharif, Arif Salman, Shilpa Bhandi, Hosam Ali Baeshen, Thodur Madapusi Balaji, Pradeep Kumar Yadalam, Saranya Varadarajan, R. Srimathi R. Radha, Kamran Habib Awan, Vikrant R. Patil, A. Thirumal Raj
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
allicin
gingival crevicular fluid
periodontitis
T lymphocytes
Online Access:https://www.mdpi.com/1422-0067/22/17/9162

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