ADAM10 Plasma and CSF Levels Are Increased in Mild Alzheimer’s Disease

ADAM10 Plasma and CSF Levels Are Increased in Mild Alzheimer’s Disease

ADAM10 is the main α-secretase that participates in the non-amyloidogenic cleavage of amyloid precursor protein (APP) in neurons, inhibiting the production of β-amyloid peptide (Aβ) in Alzheimer’s disease (AD). Strong recent evidence indicates the importance of the localization of ADAM10 for its act...

Full description

Bibliographic Details
Main Authors: Izabela Pereira Vanatabe, Rafaela Peron, Marina Mantellatto Grigoli, Silvia Pelucchi, Giulia De Cesare, Thamires Magalhães, Patricia Regina Manzine, Marcio Luiz Figueredo Balthazar, Monica Di Luca, Elena Marcello, Marcia Regina Cominetti
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
ADAM10
biomarker
Alzheimer’s disease
Online Access:https://www.mdpi.com/1422-0067/22/5/2416

Internet

https://www.mdpi.com/1422-0067/22/5/2416

Similar Items