Multiscale complexity analysis of the cardiac control identifies asymptomatic and symptomatic patients in long QT syndrome type 1.

The study assesses complexity of the cardiac control directed to the sinus node and to ventricles in long QT syndrome type 1 (LQT1) patients with KCNQ1-A341V mutation. Complexity was assessed via refined multiscale entropy (RMSE) computed over the beat-to-beat variability series of heart period (HP)...

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Main Authors: Vlasta Bari, José F Valencia, Montserrat Vallverdú, Giulia Girardengo, Andrea Marchi, Tito Bassani, Pere Caminal, Sergio Cerutti, Alfred L George, Paul A Brink, Lia Crotti, Peter J Schwartz, Alberto Porta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3976293?pdf=render