Toll-Like Receptor 4 Modulates Small Intestine Neuromuscular Function through Nitrergic and Purinergic Pathways

Toll-Like Receptor 4 Modulates Small Intestine Neuromuscular Function through Nitrergic and Purinergic Pathways

Objective: Toll-like receptors (TLRs) play a pivotal role in the homeostatic microflora-host crosstalk. TLR4-mediated modulation of both motility and enteric neuronal survival has been reported mainly for colon with limited information on the role of TLR4 in tuning structural and functional integrit...

Full description

Bibliographic Details
Main Authors: Valentina Caputi, Ilaria Marsilio, Silvia Cerantola, Mona Roozfarakh, Isabella Lante, Francesca Galuppini, Massimo Rugge, Eleonora Napoli, Cecilia Giulivi, Genny Orso, Maria Cecilia Giron
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Pharmacology
Subjects:
toll-like receptor 4
enteric nervous system
small bowel
intestinal motility
intestinal transit
innate immunity
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00350/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00350/full

Similar Items