The GAP Portion of Pseudomonas Aeruginosa Type III Secreted Toxin ExoS Upregulates Total and Surface Levels of Wild Type CFTR

The GAP Portion of Pseudomonas Aeruginosa Type III Secreted Toxin ExoS Upregulates Total and Surface Levels of Wild Type CFTR

Background: Pseudomonas aeruginosa (PA) infections account for a large percentage of fatal hospital acquired pneumonias. One of the PA Type III secreted toxin (TTST) ExoS, a bifunctional protein with N-terminal GTPase activating protein (GAP) and C-terminal ADP rybosyl transferase (ADPRT) activities...

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Bibliographic Details
Main Authors: Deepali N. Tukaye, Sang-Ho Kwon, Wiliam B. Guggino
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
ExoS-GAP
CFTR
Pseudomonas aueroginosa
Online Access:http://www.karger.com/Article/FullText/343357

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