Massive depletion of bovine leukemia virus proviral clones located in genomic transcriptionally active sites during primary infection.

Massive depletion of bovine leukemia virus proviral clones located in genomic transcriptionally active sites during primary infection.

Deltaretroviruses such as human T-lymphotropic virus type 1 (HTLV-1) and bovine leukemia virus (BLV) induce a persistent infection that remains generally asymptomatic but can also lead to leukemia or lymphoma. These viruses replicate by infecting new lymphocytes (i.e. the infectious cycle) or via cl...

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Bibliographic Details
Main Authors: Nicolas A Gillet, Gerónimo Gutiérrez, Sabrina M Rodriguez, Alix de Brogniez, Nathalie Renotte, Irene Alvarez, Karina Trono, Luc Willems
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3789779?pdf=render

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