OVOL2 Maintains the Transcriptional Program of Human Corneal Epithelium by Suppressing Epithelial-to-Mesenchymal Transition

OVOL2 Maintains the Transcriptional Program of Human Corneal Epithelium by Suppressing Epithelial-to-Mesenchymal Transition

In development, embryonic ectoderm differentiates into neuroectoderm and surface ectoderm using poorly understood mechanisms. Here, we show that the transcription factor OVOL2 maintains the transcriptional program of human corneal epithelium cells (CECs), a derivative of the surface ectoderm, and th...

Full description

Bibliographic Details
Main Authors: Koji Kitazawa, Takafusa Hikichi, Takahiro Nakamura, Kanae Mitsunaga, Azusa Tanaka, Masahiro Nakamura, Tatsuya Yamakawa, Shiori Furukawa, Mieko Takasaka, Naoki Goshima, Akira Watanabe, Keisuke Okita, Satoshi Kawasaki, Morio Ueno, Shigeru Kinoshita, Shinji Masui
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716304338

Internet

http://www.sciencedirect.com/science/article/pii/S2211124716304338

Similar Items