IL-12Rβ1 deficiency corresponding to concurrency of two diseases, mendelian susceptibility to mycobacterial disease and Crohn's disease

IL-12Rβ1 deficiency corresponding to concurrency of two diseases, mendelian susceptibility to mycobacterial disease and Crohn's disease

Background: The interleukin-12 receptor β1 (IL-12Rβ1) deficiency is a primary immunodeficiency (PID), affecting the immunological pathway of interleukin 12/interferon- γ (IL12/IFN-γ) axis and interleukin 23 receptor (IL23R). Defect in this pathway is mainly affecting the cellular immunity-related di...

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Bibliographic Details
Main Authors: Razieh Khoshnevisan, Nioosha Nekooei-marnany, Christoph Klein, Daniel Kotlarz, Mahdieh Behnam, Vajihe Ostadi, Majid Yaran, Abbas Rezaei, Roya Sherkat
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2405579419300646

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