Decavanadate Salts of Cytosine and Metformin: A Combined Experimental-Theoretical Study of Potential Metallodrugs Against Diabetes and Cancer

Decavanadate Salts of Cytosine and Metformin: A Combined Experimental-Theoretical Study of Potential Metallodrugs Against Diabetes and Cancer

Cytosine, a DNA and RNA building-block, and Metformin, the most widely prescribed drug for the treatment of Type 2 Diabetes mellitus were made to react separately with ammonium or sodium metavanadates in acidic aqueous solutions to obtain two polyoxovanadate salts with a 6:1 ratio of cation-anion. T...

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Bibliographic Details
Main Authors: Eduardo Sánchez-Lara, Samuel Treviño, Brenda L. Sánchez-Gaytán, Enrique Sánchez-Mora, María Eugenia Castro, Francisco J. Meléndez-Bustamante, Miguel A. Méndez-Rojas, Enrique González-Vergara
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Chemistry
Subjects:
decavanadate
metformin
cytosine
X-ray crystal structure
vibrational spectroscopy
51V-NMR
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2018.00402/full

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