Knockdown of Musashi RNA Binding Proteins Decreases Radioresistance but Enhances Cell Motility and Invasion in Triple-Negative Breast Cancer

Knockdown of Musashi RNA Binding Proteins Decreases Radioresistance but Enhances Cell Motility and Invasion in Triple-Negative Breast Cancer

The therapeutic potential of Musashi (MSI) RNA-binding proteins, important stemness-associated gene expression regulators, remains insufficiently understood in breast cancer. This study identifies the interplay between MSI protein expression, stem cell characteristics, radioresistance, cell invasive...

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Bibliographic Details
Main Authors: Fabian M. Troschel, Annemarie Minte, Yahia Mahmoud Ismail, Amr Kamal, Mahmoud Salah Abdullah, Sarah Hamdy Ahmed, Marie Deffner, Björn Kemper, Ludwig Kiesel, Hans Theodor Eich, Sherif Abdelaziz Ibrahim, Martin Götte, Burkhard Greve
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
musashi rna-binding proteins
breast cancer stem cells
notch
apoptosis
proliferation
radiotherapy
egfr
lifr
migration
invasiveness
Online Access:https://www.mdpi.com/1422-0067/21/6/2169

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