Mechanisms Underpinning Increased Plasma Creatinine Levels in Patients Receiving Vemurafenib for Advanced Melanoma.

Serum creatinine has been reported to increase in patients receiving Vemurafenib, yet neither the prevalence nor the mechanism of this adverse event are known.We aimed to evaluate the frequency and the mechanisms of increases in plasma creatinine level in patients receiving Vemurafenib for advanced...

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Bibliographic Details
Main Authors: Charlotte Hurabielle, Evangéline Pillebout, Thomas Stehlé, Cécile Pagès, Jennifer Roux, Pierre Schneider, Sylvie Chevret, Cendrine Chaffaut, Anne Boutten, Samia Mourah, Nicole Basset-Seguin, Emmanuelle Vidal-Petiot, Céleste Lebbé, Martin Flamant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4773169?pdf=render