p47<sup>phox</sup>-Dependent Oxidant Signalling through ASK1, MKK3/6 and MAPKs in Angiotensin II-Induced Cardiac Hypertrophy and Apoptosis

The p47<sup>phox</sup> is a key regulatory subunit of Nox2-containing NADPH oxidase (Nox2) that by generating reactive oxygen species (ROS) plays an important role in Angiotensin II (AngII)-induced cardiac hypertrophy and heart failure. However, the signalling pathways of p47<sup>p...

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Bibliographic Details
Main Authors: Fangfei Liu, Lampson M. Fan, Li Geng, Jian-Mei Li
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/10/9/1363