aMAP is a validated pipeline for registration and segmentation of high-resolution mouse brain data

Anatomical segmentation of high-resolution 3D microscopy datasets is necessary to map large samples at cellular resolution. Here the authors present a pipeline for automated mouse atlas propagation (aMAP) to segment fluorescence images of the adult mouse brain and validate it against human segmentat...

Full description

Bibliographic Details
Main Authors: Christian J. Niedworok, Alexander P. Y. Brown, M. Jorge Cardoso, Pavel Osten, Sebastien Ourselin, Marc Modat, Troy W. Margrie
Format: Article
Language:English
Published: Nature Publishing Group 2016-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11879
id doaj-84dc07594c574017bccfa315fa0d6d5f
record_format Article
spelling doaj-84dc07594c574017bccfa315fa0d6d5f2021-05-11T10:52:28ZengNature Publishing GroupNature Communications2041-17232016-07-01711910.1038/ncomms11879aMAP is a validated pipeline for registration and segmentation of high-resolution mouse brain dataChristian J. Niedworok0Alexander P. Y. Brown1M. Jorge Cardoso2Pavel Osten3Sebastien Ourselin4Marc Modat5Troy W. Margrie6The Division of Neurophysiology, MRC National Institute for Medical ResearchThe Division of Neurophysiology, MRC National Institute for Medical ResearchTranslational Imaging Group, Centre for Medical Image Computing, University College LondonCold Spring Harbor LaboratoryTranslational Imaging Group, Centre for Medical Image Computing, University College LondonTranslational Imaging Group, Centre for Medical Image Computing, University College LondonThe Division of Neurophysiology, MRC National Institute for Medical ResearchAnatomical segmentation of high-resolution 3D microscopy datasets is necessary to map large samples at cellular resolution. Here the authors present a pipeline for automated mouse atlas propagation (aMAP) to segment fluorescence images of the adult mouse brain and validate it against human segmentations.https://doi.org/10.1038/ncomms11879
collection DOAJ
language English
format Article
sources DOAJ
author Christian J. Niedworok
Alexander P. Y. Brown
M. Jorge Cardoso
Pavel Osten
Sebastien Ourselin
Marc Modat
Troy W. Margrie
spellingShingle Christian J. Niedworok
Alexander P. Y. Brown
M. Jorge Cardoso
Pavel Osten
Sebastien Ourselin
Marc Modat
Troy W. Margrie
aMAP is a validated pipeline for registration and segmentation of high-resolution mouse brain data
Nature Communications
author_facet Christian J. Niedworok
Alexander P. Y. Brown
M. Jorge Cardoso
Pavel Osten
Sebastien Ourselin
Marc Modat
Troy W. Margrie
author_sort Christian J. Niedworok
title aMAP is a validated pipeline for registration and segmentation of high-resolution mouse brain data
title_short aMAP is a validated pipeline for registration and segmentation of high-resolution mouse brain data
title_full aMAP is a validated pipeline for registration and segmentation of high-resolution mouse brain data
title_fullStr aMAP is a validated pipeline for registration and segmentation of high-resolution mouse brain data
title_full_unstemmed aMAP is a validated pipeline for registration and segmentation of high-resolution mouse brain data
title_sort amap is a validated pipeline for registration and segmentation of high-resolution mouse brain data
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2016-07-01
description Anatomical segmentation of high-resolution 3D microscopy datasets is necessary to map large samples at cellular resolution. Here the authors present a pipeline for automated mouse atlas propagation (aMAP) to segment fluorescence images of the adult mouse brain and validate it against human segmentations.
url https://doi.org/10.1038/ncomms11879
work_keys_str_mv AT christianjniedworok amapisavalidatedpipelineforregistrationandsegmentationofhighresolutionmousebraindata
AT alexanderpybrown amapisavalidatedpipelineforregistrationandsegmentationofhighresolutionmousebraindata
AT mjorgecardoso amapisavalidatedpipelineforregistrationandsegmentationofhighresolutionmousebraindata
AT pavelosten amapisavalidatedpipelineforregistrationandsegmentationofhighresolutionmousebraindata
AT sebastienourselin amapisavalidatedpipelineforregistrationandsegmentationofhighresolutionmousebraindata
AT marcmodat amapisavalidatedpipelineforregistrationandsegmentationofhighresolutionmousebraindata
AT troywmargrie amapisavalidatedpipelineforregistrationandsegmentationofhighresolutionmousebraindata
_version_ 1721447416038686720