Precision modeling of mitochondrial diseases in zebrafish via DdCBE-mediated mtDNA base editing

Precision modeling of mitochondrial diseases in zebrafish via DdCBE-mediated mtDNA base editing

Bibliographic Details
Main Authors: Jiayin Guo, Xue Zhang, Xiaoxu Chen, Haifeng Sun, Yichen Dai, Jianying Wang, Xuezhen Qian, Lei Tan, Xin Lou, Bin Shen
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-021-00307-9
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spelling doaj-84d8f74318724cf3894d45abf689ce062021-09-05T11:46:58ZengNature Publishing GroupCell Discovery2056-59682021-09-01711510.1038/s41421-021-00307-9Precision modeling of mitochondrial diseases in zebrafish via DdCBE-mediated mtDNA base editingJiayin Guo0Xue Zhang1Xiaoxu Chen2Haifeng Sun3Yichen Dai4Jianying Wang5Xuezhen Qian6Lei Tan7Xin Lou8Bin Shen9State Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityModel Animal Research Centre, Medical School of Nanjing UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityModel Animal Research Centre, Medical School of Nanjing UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical Universityhttps://doi.org/10.1038/s41421-021-00307-9
collection DOAJ
language English
format Article
sources DOAJ
author Jiayin Guo
Xue Zhang
Xiaoxu Chen
Haifeng Sun
Yichen Dai
Jianying Wang
Xuezhen Qian
Lei Tan
Xin Lou
Bin Shen
spellingShingle Jiayin Guo
Xue Zhang
Xiaoxu Chen
Haifeng Sun
Yichen Dai
Jianying Wang
Xuezhen Qian
Lei Tan
Xin Lou
Bin Shen
Precision modeling of mitochondrial diseases in zebrafish via DdCBE-mediated mtDNA base editing
Cell Discovery
author_facet Jiayin Guo
Xue Zhang
Xiaoxu Chen
Haifeng Sun
Yichen Dai
Jianying Wang
Xuezhen Qian
Lei Tan
Xin Lou
Bin Shen
author_sort Jiayin Guo
title Precision modeling of mitochondrial diseases in zebrafish via DdCBE-mediated mtDNA base editing
title_short Precision modeling of mitochondrial diseases in zebrafish via DdCBE-mediated mtDNA base editing
title_full Precision modeling of mitochondrial diseases in zebrafish via DdCBE-mediated mtDNA base editing
title_fullStr Precision modeling of mitochondrial diseases in zebrafish via DdCBE-mediated mtDNA base editing
title_full_unstemmed Precision modeling of mitochondrial diseases in zebrafish via DdCBE-mediated mtDNA base editing
title_sort precision modeling of mitochondrial diseases in zebrafish via ddcbe-mediated mtdna base editing
publisher Nature Publishing Group
series Cell Discovery
issn 2056-5968
publishDate 2021-09-01
url https://doi.org/10.1038/s41421-021-00307-9
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AT xiaoxuchen precisionmodelingofmitochondrialdiseasesinzebrafishviaddcbemediatedmtdnabaseediting
AT haifengsun precisionmodelingofmitochondrialdiseasesinzebrafishviaddcbemediatedmtdnabaseediting
AT yichendai precisionmodelingofmitochondrialdiseasesinzebrafishviaddcbemediatedmtdnabaseediting
AT jianyingwang precisionmodelingofmitochondrialdiseasesinzebrafishviaddcbemediatedmtdnabaseediting
AT xuezhenqian precisionmodelingofmitochondrialdiseasesinzebrafishviaddcbemediatedmtdnabaseediting
AT leitan precisionmodelingofmitochondrialdiseasesinzebrafishviaddcbemediatedmtdnabaseediting
AT xinlou precisionmodelingofmitochondrialdiseasesinzebrafishviaddcbemediatedmtdnabaseediting
AT binshen precisionmodelingofmitochondrialdiseasesinzebrafishviaddcbemediatedmtdnabaseediting
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