Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing

Isotope tracer administration for probing metabolism in vivo is important to assess metabolic functions in a relevant physiological setting. Here, the authors report a non-invasive method of administering 13C6- glucose to mouse models via liquid diet feeding to achieve deep metabolic network coverag...

Full description

Bibliographic Details
Main Authors:	Ramon C. Sun, Teresa W.-M. Fan, Pan Deng, Richard M. Higashi, Andrew N. Lane, Anh-Thu Le, Timothy L. Scott, Qiushi Sun, Marc O. Warmoes, Ye Yang
Format:	Article
Language:	English
Published:	Nature Publishing Group 2017-11-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-017-01518-z

id	doaj-84d4323985664c0fb540d359fc803901
record_format	Article
spelling	doaj-84d4323985664c0fb540d359fc8039012021-05-11T07:18:49ZengNature Publishing GroupNature Communications2041-17232017-11-018111010.1038/s41467-017-01518-zNoninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracingRamon C. Sun0Teresa W.-M. Fan1Pan Deng2Richard M. Higashi3Andrew N. Lane4Anh-Thu Le5Timothy L. Scott6Qiushi Sun7Marc O. Warmoes8Ye Yang9Center for Environmental and Systems Biochemistry, University of KentuckyCenter for Environmental and Systems Biochemistry, University of KentuckyCenter for Environmental and Systems Biochemistry, University of KentuckyCenter for Environmental and Systems Biochemistry, University of KentuckyCenter for Environmental and Systems Biochemistry, University of KentuckyDepartment of Surgery, University of KentuckyCenter for Environmental and Systems Biochemistry, University of KentuckyCenter for Environmental and Systems Biochemistry, University of KentuckyCenter for Environmental and Systems Biochemistry, University of KentuckyCenter for Environmental and Systems Biochemistry, University of KentuckyIsotope tracer administration for probing metabolism in vivo is important to assess metabolic functions in a relevant physiological setting. Here, the authors report a non-invasive method of administering 13C6- glucose to mouse models via liquid diet feeding to achieve deep metabolic network coverage.https://doi.org/10.1038/s41467-017-01518-z
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Ramon C. Sun Teresa W.-M. Fan Pan Deng Richard M. Higashi Andrew N. Lane Anh-Thu Le Timothy L. Scott Qiushi Sun Marc O. Warmoes Ye Yang
spellingShingle	Ramon C. Sun Teresa W.-M. Fan Pan Deng Richard M. Higashi Andrew N. Lane Anh-Thu Le Timothy L. Scott Qiushi Sun Marc O. Warmoes Ye Yang Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing Nature Communications
author_facet	Ramon C. Sun Teresa W.-M. Fan Pan Deng Richard M. Higashi Andrew N. Lane Anh-Thu Le Timothy L. Scott Qiushi Sun Marc O. Warmoes Ye Yang
author_sort	Ramon C. Sun
title	Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing
title_short	Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing
title_full	Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing
title_fullStr	Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing
title_full_unstemmed	Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing
title_sort	noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2017-11-01
description	Isotope tracer administration for probing metabolism in vivo is important to assess metabolic functions in a relevant physiological setting. Here, the authors report a non-invasive method of administering 13C6- glucose to mouse models via liquid diet feeding to achieve deep metabolic network coverage.
url	https://doi.org/10.1038/s41467-017-01518-z
work_keys_str_mv	AT ramoncsun noninvasiveliquiddietdeliveryofstableisotopesintomousemodelsfordeepmetabolicnetworktracing AT teresawmfan noninvasiveliquiddietdeliveryofstableisotopesintomousemodelsfordeepmetabolicnetworktracing AT pandeng noninvasiveliquiddietdeliveryofstableisotopesintomousemodelsfordeepmetabolicnetworktracing AT richardmhigashi noninvasiveliquiddietdeliveryofstableisotopesintomousemodelsfordeepmetabolicnetworktracing AT andrewnlane noninvasiveliquiddietdeliveryofstableisotopesintomousemodelsfordeepmetabolicnetworktracing AT anhthule noninvasiveliquiddietdeliveryofstableisotopesintomousemodelsfordeepmetabolicnetworktracing AT timothylscott noninvasiveliquiddietdeliveryofstableisotopesintomousemodelsfordeepmetabolicnetworktracing AT qiushisun noninvasiveliquiddietdeliveryofstableisotopesintomousemodelsfordeepmetabolicnetworktracing AT marcowarmoes noninvasiveliquiddietdeliveryofstableisotopesintomousemodelsfordeepmetabolicnetworktracing AT yeyang noninvasiveliquiddietdeliveryofstableisotopesintomousemodelsfordeepmetabolicnetworktracing
_version_	1721452482631041024

Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing

Similar Items