Age-adjusted association of homologous recombination genes with ovarian cancer using clinical exomes as controls

Age-adjusted association of homologous recombination genes with ovarian cancer using clinical exomes as controls

Abstract Background Genes in the homologous recombination pathway have shown varying results in the literature regarding ovarian cancer (OC) association. Recent case-control studies have used allele counts alone to quantify genetic associations with cancer. Methods A retrospective case-control study...

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Bibliographic Details
Main Authors: Kevin J. Arvai, Maegan E. Roberts, Rebecca I. Torene, Lisa R. Susswein, Megan L. Marshall, Zhancheng Zhang, Natalie J. Carter, Lauren Yackowski, Erica S. Rinella, Rachel T. Klein, Kathleen S. Hruska, Kyle Retterer
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Ovarian Cancer
BRIP1
Exome sequencing
Online Access:http://link.springer.com/article/10.1186/s13053-019-0119-3

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