Integration of Fungus-Specific CandA-C1 into a Trimeric CandA Complex Allowed Splitting of the Gene for the Conserved Receptor Exchange Factor of CullinA E3 Ubiquitin Ligases in Aspergilli

Integration of Fungus-Specific CandA-C1 into a Trimeric CandA Complex Allowed Splitting of the Gene for the Conserved Receptor Exchange Factor of CullinA E3 Ubiquitin Ligases in Aspergilli

Aspergillus species are important for biotechnological applications, like the production of citric acid or antibacterial agents. Aspergilli can cause food contamination or invasive aspergillosis to immunocompromised humans or animals. Specific treatment is difficult due to limited drug targets and e...

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Bibliographic Details
Main Authors: Anna M. Köhler, Rebekka Harting, Annika E. Langeneckert, Oliver Valerius, Jennifer Gerke, Cindy Meister, Anja Strohdiek, Gerhard H. Braus
Format: Article
Language:English
Published: American Society for Microbiology 2019-06-01
Series:mBio
Subjects:
Aspergillus fumigatus
Aspergillus nidulans
COP9 signalosome
Cand1
Cullin-RING ubiquitin ligase
Nedd8
asexual development
protein complex
protein degradation
secondary metabolism
sexual development
spore germination
Online Access:https://doi.org/10.1128/mBio.01094-19

Internet

https://doi.org/10.1128/mBio.01094-19

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