The Lysozyme Inhibitor Thionine Acetate Is Also an Inhibitor of the Soluble Lytic Transglycosylase Slt35 from <i>Escherichia coli</i>

The Lysozyme Inhibitor Thionine Acetate Is Also an Inhibitor of the Soluble Lytic Transglycosylase Slt35 from <i>Escherichia coli</i>

Lytic transglycosylases such as Slt35 from <i>E. coli</i> are enzymes involved in bacterial cell wall remodelling and recycling, which represent potential targets for novel antibacterial agents. Here, we investigated a series of known glycosidase inhibitors for their ability to inhibit S...

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Bibliographic Details
Main Authors: Aysha B. Mezoughi, Chiara M. Costanzo, Gregor M. Parker, Enas M. Behiry, Alan Scott, Andrew C. Wood, Sarah E. Adams, Richard B. Sessions, E. Joel Loveridge
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
lytic transglycosylase
thionine acetate
enzyme inhibition
antibacterial
Online Access:https://www.mdpi.com/1420-3049/26/14/4189

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