Distinct epigenetic signatures between adult-onset and late-onset depression

Abstract The heterogeneity of major depressive disorder (MDD) is attributed to the fact that diagnostic criteria (e.g., DSM-5) are only based on clinical symptoms. The discovery of blood biomarkers has the potential to change the diagnosis of MDD. The purpose of this study was to identify blood biom...

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Bibliographic Details
Main Authors: Hirotaka Yamagata, Hiroyuki Ogihara, Koji Matsuo, Shusaku Uchida, Ayumi Kobayashi, Tomoe Seki, Masaaki Kobayashi, Kenichiro Harada, Chong Chen, Shigeo Miyata, Masato Fukuda, Masahiko Mikuni, Yoshihiko Hamamoto, Yoshifumi Watanabe, Shin Nakagawa
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81758-8