MTHFR C677T predisposes to POAG but not to PACG in a North Indian population: a case control study.

MTHFR C677T predisposes to POAG but not to PACG in a North Indian population: a case control study.

Hyperhomocysteinemia induced by the C677T genetic variant in MTHFR (methylenetetrahydrofolate reductase) has been implicated in neuronal cell death of retinal ganglion cells (RGC), which is a characteristic feature of glaucoma. However, association of MTHFR C677T with glaucoma has been controversial...

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Main Authors: Shashank Gupta, Pradeep Kumar Bhaskar, Ritu Bhardwaj, Abhishek Chandra, Vidya Nair Chaudhry, Prashaant Chaudhry, Akhtar Ali, Ashim Mukherjee, Mousumi Mutsuddi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4108368?pdf=render

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