Bim and Bmf synergize to induce apoptosis in Neisseria gonorrhoeae infection.
Bcl-2 family proteins including the pro-apoptotic BH3-only proteins are central regulators of apoptotic cell death. Here we show by a focused siRNA miniscreen that the synergistic action of the BH3-only proteins Bim and Bmf is required for apoptosis induced by infection with Neisseria gonorrhoeae (N...
Main Authors: | Oliver Kepp, Kathleen Gottschalk, Yuri Churin, Krishnaraj Rajalingam, Volker Brinkmann, Nikolaus Machuy, Guido Kroemer, Thomas Rudel |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-03-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2654407?pdf=render |
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