Linking Cancer Stem Cell Plasticity to Therapeutic Resistance-Mechanism and Novel Therapeutic Strategies in Esophageal Cancer

Linking Cancer Stem Cell Plasticity to Therapeutic Resistance-Mechanism and Novel Therapeutic Strategies in Esophageal Cancer

Esophageal cancer (EC) is an aggressive form of cancer, including squamous cell carcinoma (ESCC) and adenocarcinoma (EAC) as two predominant histological subtypes. Accumulating evidence supports the existence of cancer stem cells (CSCs) able to initiate and maintain EAC or ESCC. In this review, we a...

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Bibliographic Details
Main Authors: Chenghui Zhou, Ningbo Fan, Fanyu Liu, Nan Fang, Patrick S. Plum, René Thieme, Ines Gockel, Sascha Gromnitza, Axel M. Hillmer, Seung-Hun Chon, Hans A. Schlösser, Christiane J. Bruns, Yue Zhao
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
esophageal cancer
heterogeneity
cancer stem cell
plasticity
therapeutic resistance
Online Access:https://www.mdpi.com/2073-4409/9/6/1481

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