A randomized, placebo controlled pilot trial of botulinum toxin for paratonic rigidity in people with advanced cognitive impairment.

A randomized, placebo controlled pilot trial of botulinum toxin for paratonic rigidity in people with advanced cognitive impairment.

Evaluate safety and efficacy of Incobotulinumtoxin A in elderly patients with dementia and paratonia.University-affiliated hospital, spasticity management Clinic.Ten subjects were enrolled.1) severe cognitive impairment 2) diagnosis of Alzheimer's disease, vascular dementia, or frontotemporal d...

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Bibliographic Details
Main Authors: Galit Kleiner-Fisman, Edwin Khoo, Nikohl Moncrieffe, Triina Forbell, Pearl Gryfe, David Fisman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4275182?pdf=render

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