Brucellosis vaccines: assessment of Brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export.

BACKGROUND: The brucellae are facultative intracellular bacteria that cause brucellosis, one of the major neglected zoonoses. In endemic areas, vaccination is the only effective way to control this disease. Brucella melitensis Rev 1 is a vaccine effective against the brucellosis of sheep and goat ca...

Full description

Bibliographic Details
Main Authors: David González, María-Jesús Grilló, María-Jesús De Miguel, Tara Ali, Vilma Arce-Gorvel, Rose-May Delrue, Raquel Conde-Alvarez, Pilar Muñoz, Ignacio López-Goñi, Maite Iriarte, Clara-M Marín, Andrej Weintraub, Göran Widmalm, Michel Zygmunt, Jean-Jacques Letesson, Jean-Pierre Gorvel, José-María Blasco, Ignacio Moriyón
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2453230?pdf=render