A model for focal seizure onset, propagation, evolution, and progression

A model for focal seizure onset, propagation, evolution, and progression

We developed a neural network model that can account for major elements common to human focal seizures. These include the tonic-clonic transition, slow advance of clinical semiology and corresponding seizure territory expansion, widespread EEG synchronization, and slowing of the ictal rhythm as the...

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Bibliographic Details
Main Authors: Jyun-you Liou, Elliot H Smith, Lisa M Bateman, Samuel L Bruce, Guy M McKhann, Robert R Goodman, Ronald G Emerson, Catherine A Schevon, LF Abbott
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-03-01
Series:eLife
Subjects:
epilepsy
seizure models
traveling waves
focal seizure
synaptic plasticity
EEG
Online Access:https://elifesciences.org/articles/50927

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