Hyperleukocytosis and Leukostasis in Acute Myeloid Leukemia: Can a Better Understanding of the Underlying Molecular Pathophysiology Lead to Novel Treatments?

Up to 18% of patients with acute myeloid leukemia (AML) present with a white blood cell (WBC) count of greater than 100,000/µL, a condition that is frequently referred to as hyperleukocytosis. Hyperleukocytosis has been associated with an adverse prognosis and a higher incidence of life-threatening...

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Bibliographic Details
Main Authors: Jan Philipp Bewersdorf, Amer M. Zeidan
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cells
Subjects:
AML
Online Access:https://www.mdpi.com/2073-4409/9/10/2310